A rare but important cause of fulminant hepatic failure

A rare but important cause of fulminant hepatic failure

A 79 year-old Caucasian man presented to our institution with jaundice and dark urine having fallen from a ladder in his stables three days prior to admission. The fall had left him with some discomfort for which he had self-medicated with paracetamol. He denied having exceeded the recommended dose of paracetamol. There was no past medical history of liver disease, illicit drug use, drugs known...

Acute fulminant hepatic failure due to colchicine – a rare manifestation of Gloriosa superba poisoning.

Glyphosate Poisoning with Acute Fulminant Hepatic Failure

Background: Glyphosate containing herbicides are widely used the world over. They are marketed as nontoxic to humans, but numerous studies have showed that these glyphosate-based herbicides (GlySH) can cause multiorgan damage.1 Recent reports of animal studies on rats have raised a doubt of liver damage after long term exposure to GlySH. Case Presentation: a young male had chronic exposure to G...

Fulminant hepatic failure due to metastatic choroidal melanoma

Fulminant Hepatic Failure

Acute liver failure (ALF), also known as fulminant hepatic failure (FHF), embraces a spectrum of clinical entities characterized by acute liver injury, severe hepatocellular dysfunction, and hepatic encephalopathy. This condition is uncommon but not rare; it affects approximately 2000 to 2800 people annually in the United States, with a mortality of 3.5 per million despite intensive support. Lo...